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Chemopreventive effect of the polysaccharides from Grifola frondosa in colitis-associated colorectal cancer by modulating the Wnt/β-catenin/GSK-3β signaling pathway in C57BL/6 mice
- Source :
- Journal of Functional Foods, Vol 63, Iss , Pp - (2019)
- Publication Year :
- 2019
- Publisher :
- Elsevier, 2019.
-
Abstract
- The aim of this study was to analyze the preventive effect of water-soluble polysaccharides in the maitake mushrooms (Grifola frondosa) fruiting body (GFP) on colon cancer in high-fat (HF) mice and WIDR cells. In vivo, the administration of GFP decreased colon myeloperoxidase (MPO) activity and disease activity index (DAI) compared with HF group (P
Details
- Language :
- English
- ISSN :
- 17564646
- Volume :
- 63
- Issue :
- -
- Database :
- Directory of Open Access Journals
- Journal :
- Journal of Functional Foods
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.3a18096c16464fe4b31168390dfcb2d2
- Document Type :
- article
- Full Text :
- https://doi.org/10.1016/j.jff.2019.103578