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First-line treatment of chronic lymphocytic leukemia with ibrutinib plus obinutuzumab versus chlorambucil plus obinutuzumab: final analysis of the randomized, phase III iLLUMINATE trial

Authors :
Carol Moreno
Richard Greil
Fatih Demirkan
Alessandra Tedeschi
Bertrand Anz
Loree Larratt
Martin Simkovic
Jan Novak
Vladimir Strugov
Devinder Gill
John G. Gribben
Kevin Kwei
Sandra Dai
Emily Hsu
James P. Dean
Ian W. Flinn
Source :
Haematologica, Vol 107, Iss 9 (2022)
Publication Year :
2022
Publisher :
Ferrata Storti Foundation, 2022.

Abstract

iLLUMINATE is a randomized, open-label phase III study of ibrutinib plus obinutuzumab (n=113) versus chlorambucil plus obinutuzumab (n=116) as first-line therapy for patients with chronic lymphocytic leukemia or small lymphocytic lymphoma. Eligible patients were aged ≥65 years, or

Details

Language :
English
ISSN :
03906078 and 15928721
Volume :
107
Issue :
9
Database :
Directory of Open Access Journals
Journal :
Haematologica
Publication Type :
Academic Journal
Accession number :
edsdoj.39c8b0aa684d82a347ea24d5b709ac
Document Type :
article
Full Text :
https://doi.org/10.3324/haematol.2021.279012