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Enrichment and identification of Δ9-Tetrahydrocannabinolic acid synthase from Pichia pastoris culture supernatants

Authors :
Kerstin Lange
Ansgar Poetsch
Andreas Schmid
Mattijs K. Julsing
Source :
Data in Brief, Vol 4, Iss C, Pp 641-649 (2015)
Publication Year :
2015
Publisher :
Elsevier, 2015.

Abstract

This data article refers to the report Δ9-Tetrahydrocannabinolic acid synthase (THCAS) production in Pichia pastoris enables chemical synthesis of cannabinoids (Lange et. al. 2015) [2]. THCAS was produced on a 2 L lab scale using recombinant P. pastoris KM71 KE1. Enrichment of THCAS as a technically pure enzyme was realized using dialysis and cationic exchange chromatography. nLC-ESI-MS/MS analysis identified THCAS in different fractions obtained by cationic exchange chromatography.

Details

Language :
English
ISSN :
23523409
Volume :
4
Issue :
C
Database :
Directory of Open Access Journals
Journal :
Data in Brief
Publication Type :
Academic Journal
Accession number :
edsdoj.398e4a5b20b847dfa0c3e415f10b09d0
Document Type :
article
Full Text :
https://doi.org/10.1016/j.dib.2015.07.033