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Post-myocardial infarction heart failure dysregulates the bone vascular niche

Authors :
Jedrzej Hoffmann
Guillermo Luxán
Wesley Tyler Abplanalp
Simone-Franziska Glaser
Tina Rasper
Ariane Fischer
Marion Muhly-Reinholz
Michael Potente
Birgit Assmus
David John
Andreas Michael Zeiher
Stefanie Dimmeler
Source :
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

Hematopoiesis influences the progression of cardiovascular disease, yet the influence of cardiovascular disease on the bone vasculature is unknown. Hoffmann, Luxán, Abplanalp et al. describe the response of the bone cell composition to myocardial infarction and provide a rationale for using anti-inflammatory therapies to prevent the deterioration of the bone vascular niche

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.398da0beec4046aba06db75788ef5a98
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-021-24045-4