Back to Search Start Over

Structure of human spermine oxidase in complex with a highly selective allosteric inhibitor

Authors :
Elsie Diaz
Suraj Adhikary
Armand W. J. W. Tepper
Daniel Riley
Rodrigo Ortiz-Meoz
Daniel Krosky
Christophe Buyck
Carolina Martinez Lamenca
Josep Llaveria
Lichao Fang
Jay H. Kalin
Vincent N. A. Klaren
Shorouk Fahmy
Paul L. Shaffer
Robert Kirkpatrick
Rodrigo J. Carbajo
Maren Thomsen
Antonietta Impagliazzo
Source :
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Rational engineering of human spermine oxidase yields crystallizable structures and the design of an allosteric inhibitor.

Subjects

Subjects :
Biology (General)
QH301-705.5

Details

Language :
English
ISSN :
23993642
Volume :
5
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Communications Biology
Publication Type :
Academic Journal
Accession number :
edsdoj.391009d10cb04621862722699df90a61
Document Type :
article
Full Text :
https://doi.org/10.1038/s42003-022-03735-9