Back to Search Start Over

Genomic landscape and chronological reconstruction of driver events in multiple myeloma

Authors :
Francesco Maura
Niccoló Bolli
Nicos Angelopoulos
Kevin J. Dawson
Daniel Leongamornlert
Inigo Martincorena
Thomas J. Mitchell
Anthony Fullam
Santiago Gonzalez
Raphael Szalat
Federico Abascal
Bernardo Rodriguez-Martin
Mehmet Kemal Samur
Dominik Glodzik
Marco Roncador
Mariateresa Fulciniti
Yu Tzu Tai
Stephane Minvielle
Florence Magrangeas
Philippe Moreau
Paolo Corradini
Kenneth C. Anderson
Jose M. C. Tubio
David C. Wedge
Moritz Gerstung
Hervé Avet-Loiseau
Nikhil Munshi
Peter J. Campbell
Source :
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Publication Year :
2019
Publisher :
Nature Portfolio, 2019.

Abstract

Multiple myeloma evolves continuously. Here the authors chronologically reconstruct driver events in multiple myeloma, noting a limited repertoire of initiating driver events that shape the evolutionary trajectory of the disease.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
10
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.38608a486ef471e8da57b4ab94d19b3
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-019-11680-1