Back to Search Start Over

Pathoimmunological analyses of fatal E11 infection in premature infants

Authors :
Wei Luo
Lixia Wang
Zhengrong Chen
Ming Liu
Yixue Zhao
Yucan Wu
Bing Huang
Ping Wang
Source :
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Publication Year :
2024
Publisher :
Frontiers Media S.A., 2024.

Abstract

E11 causes acute fulminant hepatitis in newborns. We investigated the pathological changes of different tissues from premature male twins who died due to E11 infection. The E11 expression level was higher in the liver than in other tissues. IP10 was upregulated in liver tissue in the patient group, and might be regulated by IFNAR and IRF7, whereas IFNα was regulated by IFNAR or IRF5.

Details

Language :
English
ISSN :
22352988
Volume :
14
Database :
Directory of Open Access Journals
Journal :
Frontiers in Cellular and Infection Microbiology
Publication Type :
Academic Journal
Accession number :
edsdoj.380a2b0457114a68a193a2dd014c6cae
Document Type :
article
Full Text :
https://doi.org/10.3389/fcimb.2024.1391824