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Disease-associated gut microbiome and metabolome changes in patients with chronic obstructive pulmonary disease

Authors :
Kate L. Bowerman
Saima Firdous Rehman
Annalicia Vaughan
Nancy Lachner
Kurtis F. Budden
Richard Y. Kim
David L. A. Wood
Shaan L. Gellatly
Shakti D. Shukla
Lisa G. Wood
Ian A. Yang
Peter A. Wark
Philip Hugenholtz
Philip M. Hansbro
Source :
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Publication Year :
2020
Publisher :
Nature Portfolio, 2020.

Abstract

Chronic obstructive pulmonary disease (COPD) is a progressing disease, with lung but not gut microbiota implicated in its etiology. Here the authors compare the stool from patients with COPD and healthy controls to find specific gut bacteria and metabolites associated with active disease, thereby hinting at a potential role for the gut microbiome in COPD.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
11
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.37d126ac6bf4df5ae3b32232a535530
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-020-19701-0