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A hierarchy of biomolecular proportional-integral-derivative feedback controllers for robust perfect adaptation and dynamic performance

Authors :
Maurice Filo
Sant Kumar
Mustafa Khammash
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

The design of feedback biomolecular controllers is essential to synthetically regulate biological processes in a robust and timely fashion. Here the authors introduce a wide array of biomolecular Proportional-Integral-Derivative (PID) controllers that are capable of enhancing stability and dynamic performance, and also reducing stochastic noise.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.37a5d5cf644f4e810ca1574748f346
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-29640-7