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Novel indole diketopiperazine stereoisomers from a marine-derived fungus Aspergillus sp.

Authors :
Xinyang Li
Jinzhong Xu
Pinmei Wang
Wanjing Ding
Source :
Mycology, Vol 14, Iss 1, Pp 1-10 (2023)
Publication Year :
2023
Publisher :
Taylor & Francis Group, 2023.

Abstract

ABSTRACTFour dimeric diketopiperazine stereoisomers (1–4) including two new ones (1–2) had been isolated from the culture broth of one marine-derived fungus Aspergillus sp. Z3, which was found in the gut of a marine isopod Ligia exotica. The planner structures and absolute configurations of the new compounds were determined by combination of NMR, HRESIMS, electronic circular dichroism calculation, Marfey’s method as well as single-crystal X-ray diffraction. Their cytotoxicity against the prostate cancer PC3 cell line was assayed by the MTT method.

Details

Language :
English
ISSN :
21501203 and 21501211
Volume :
14
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Mycology
Publication Type :
Academic Journal
Accession number :
edsdoj.37a130fc3ece4bbbb8aa0e92a1d11d5f
Document Type :
article
Full Text :
https://doi.org/10.1080/21501203.2022.2069173