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Diagnostic significance of paradoxical left ventricular hypertrophy in detecting cardiac amyloidosis

Authors :
Shingo Ota
Yasuhiro Izumiya
Ryoko Kitada
Takahiro Nishi
Akira Taruya
Teruaki Wada
Masahiro Takahata
Yuichi Ozaki
Manabu Kashiwagi
Yasutsugu Shiono
Akio Kuroi
Kazushi Takemoto
Takashi Tanimoto
Hironori Kitabata
Daiju Fukuda
Atsushi Tanaka
Source :
International Journal of Cardiology: Heart & Vasculature, Vol 49, Iss , Pp 101279- (2023)
Publication Year :
2023
Publisher :
Elsevier, 2023.

Abstract

Background: Cardiac amyloidosis (CA) progresses rapidly with a poor prognosis. Therefore, methods for early diagnosis that are easily accessible in any hospital, are required. We hypothesized that based on the pathology of CA, morphological left ventricular hypertrophy (LVH) without electrical augmentation, namely paradoxical LVH, could be used to diagnose CA. This study aimed to investigate whether paradoxical LVH has diagnostic significance in identifying CA in patients with LVH. Methods: Patients who presented with left ventricular (LV) wall thickness ≥ 12 mm on cardiac magnetic resonance (CMR) were enrolled from a multicentre CMR registry. Paradoxical LVH was defined as a LV wall thickness ≥ 12 mm on CMR, SV1 + RV5

Details

Language :
English
ISSN :
23529067
Volume :
49
Issue :
101279-
Database :
Directory of Open Access Journals
Journal :
International Journal of Cardiology: Heart & Vasculature
Publication Type :
Academic Journal
Accession number :
edsdoj.373eccb005fd4b34bb4771823f9ebbaf
Document Type :
article
Full Text :
https://doi.org/10.1016/j.ijcha.2023.101279