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Predictive value of C-reactive protein/albumin ratio for no-reflow in patients with non-ST-elevation myocardial infarction

Authors :
Aydın Rodi Tosu
Tufan Çinar
Muhsin Kalyoncuoğlu
Halil İbrahim Biter
Sinem Çakal
Beytullah Çakal
Murat Selçuk
Erdal Belen
Mehmet Mustafa Can
Source :
Journal of Cardiovascular and Thoracic Research, Vol 14, Iss 4, Pp 214-219 (2022)
Publication Year :
2022
Publisher :
Tabriz University of Medical Sciences, 2022.

Abstract

Introduction: The focus of this research was to explore the link between CRP (C-reactive protein) /albumin ratio (CAR), a novel inflammatory response marker, and no-reflow (NR) phenomena in non-ST elevation myocardial infarction (non-STEMI) patients during percutaneous coronary intervention (PCI). Methods: The current study recruited 209 non-STEMI participants who underwent PCI. The patients were divided into two groups based on their post-intervention Thrombolysis in Myocardial Infarction (TIMI) flow grade; those with and without NR. Results: In all, 30 non-STEMI patients (6.9%) had NR after PCI. CAR values were substantially greater in the NR group. The CAR was identified to be a determinant of the NR (OR: 1.250, 95% CI: 1.033-1.513, P=0.02), although CRP and albumin were not independently related with NR in the multivariate analysis. In our investigation, low density lipoprotein-cholesterol levels and high thrombus burden were also predictors of the occurrence of NR. According to receiver operating characteristic curve evaluation, the optimal value of CAR was>1.4 with 60% sensitivity and 47% specificity in detecting NR in non-STEMI patients following PCI. Conclusion: To the best of knowledge, this is the first investigation to demonstrate that the CAR, a new and useful inflammatory marker, can be utilized as a predictor of NR in patients with non-STEMI prior to PCI.

Details

Language :
English
ISSN :
20085117 and 20086830
Volume :
14
Issue :
4
Database :
Directory of Open Access Journals
Journal :
Journal of Cardiovascular and Thoracic Research
Publication Type :
Academic Journal
Accession number :
edsdoj.36e8360e0ebf44b1bc57f97b1980b4dd
Document Type :
article
Full Text :
https://doi.org/10.34172/jcvtr.2022.30549