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Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants
- Source :
- Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)
- Publication Year :
- 2018
- Publisher :
- Nature Portfolio, 2018.
-
Abstract
- Prostate cancer (PrCa) involves a large heritable genetic component. Here, the authors perform multivariate fine-mapping of known PrCa GWAS loci, identifying variants enriched for biological function, explaining more familial relative risk, and with potential application in clinical risk profiling.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 9
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.36e01625dae94bd89d2103af9c540d34
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-018-04109-8