Back to Search
Start Over
Combined Aerobic and Resistance Exercise Training Reduces Circulating Apolipoprotein J Levels and Improves Insulin Resistance in Postmenopausal Diabetic Women
- Source :
- Diabetes & Metabolism Journal, Vol 44, Iss 1, Pp 103-112 (2020)
- Publication Year :
- 2020
- Publisher :
- Korean Diabetes Association, 2020.
-
Abstract
- BackgroundCirculating apolipoprotein J (ApoJ) is closely associated with insulin resistance; however, the effect of exercise on circulating ApoJ levels and the association of ApoJ with metabolic indices remain unknown. Here, we investigated whether a combined exercise can alter the circulating ApoJ level, and whether these changes are associated with metabolic indices in patients with type 2 diabetes mellitus.MethodsPostmenopausal women with type 2 diabetes mellitus were randomly assigned into either an exercise (EXE, n=30) or control (CON, n=15) group. Participants in the EXE group were enrolled in a 12-week program consisting of a combination of aerobic and resistance exercises. At baseline, 4, 8, and 12 weeks, body composition and metabolic parameters including homeostatic model assessment of insulin resistance (HOMA-IR) and serum ApoJ levels were assessed.ResultsIn the EXE group, ApoJ levels decreased 26.3% and 19.4%, relative to baseline, at 8 and 12 weeks, respectively. Between-group differences were significant at 8 and 12 weeks (P
Details
- Language :
- English
- ISSN :
- 22336079 and 22336087
- Volume :
- 44
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Diabetes & Metabolism Journal
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.36098adb3cf842ab8d3eb66b9a064a3e
- Document Type :
- article
- Full Text :
- https://doi.org/10.4093/dmj.2018.0160