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Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients

Authors :
Li Chen
Liu Yang
Ling Yao
Xia-Ying Kuang
Wen-Jia Zuo
Shan Li
Feng Qiao
Yi-Rong Liu
Zhi-Gang Cao
Shu-Ling Zhou
Xiao-Yan Zhou
Wen-Tao Yang
Jin-Xiu Shi
Wei Huang
Xin Hu
Zhi-Ming Shao
Source :
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Publication Year :
2018
Publisher :
Nature Portfolio, 2018.

Abstract

The PI3K pathway is altered across various cancer types. Here the authors use amplicon exon sequencing to analyze the landscape of somatic mutations affecting the PI3K pathway specifically in breast cancer patients in China.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.35be9cbfd9d943158a629a540eb68b22
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-018-03867-9