Changes of retinal microcirculation in postnatal patients with pregnancy-induced hypertension based on OCTA

AIM: To quantitatively analyze the changes of retinal microcirculation in patients with pregnancy-induced hypertension(PIH)syndrome who have delivered after more than 6mo by using optical coherence tomography angiography(OCTA).METHODS: In this study, a total of 19 females with PIH, 23 healthy pregnant women and 19 control non pregnant women(CNPW)were recruited. Ocular examinations including diopter, best corrected visual acuity and axial length were measured, respectively. OCTA was used to measure the optic nerve head and macular blood flow parameters, nerve fiber layer and choroidal thickness of the three groups. The data of pregnant patients were collected more than 6mo after delivery. All statistical analyses were performed in the SPSS20.0, and single factor analysis of variance was used to analyze inter-group differences of retinal microcirculation related parameters among the three groups.RESULTS: Foveal avascular zone(FAZ)of the PIH group was significantly larger than that of the HPW and CNPW groups(all P