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High prevalence of Pentatrichomonas hominis infection in gastrointestinal cancer patients
- Source :
- Parasites & Vectors, Vol 12, Iss 1, Pp 1-9 (2019)
- Publication Year :
- 2019
- Publisher :
- BMC, 2019.
-
Abstract
- Abstract Background Pentatrichomonas hominis is a flagellated protozoan that inhabits the large intestine of humans. Although several protozoans have been proposed to have a role in cancer progression, little is known about the epidemiology of P. hominis infection in cancer patients. Methods To determine the prevalence of P. hominis in patients with digestive system malignancies, we collected 195 and 142 fecal samples from gastrointestinal cancer patients and residents without any complaints related to the digestive system, respectively. Each sample was detected for the presence of P. hominis by nested PCR amplifying the internal transcribed spacer (ITS) region and partial 18S rRNA gene. Results A significantly higher prevalence of P. hominis was found in cancer patients than that in the control population (41.54 vs 9.15%, χ 2 = 42.84, df = 1, P
Details
- Language :
- English
- ISSN :
- 17563305
- Volume :
- 12
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Parasites & Vectors
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.353d36fee1e044b4adeb35d187359ade
- Document Type :
- article
- Full Text :
- https://doi.org/10.1186/s13071-019-3684-4