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Safety and efficacy of a feed additive consisting of 6‐phytase produced by Komagataella phaffii CGMCC 7.370 (VTR‐phytase powder/liquid) for all pigs and all avian species (Victory Enzymes GmbH)

Authors :
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
Vasileios Bampidis
Giovanna Azimonti
Maria de Lourdes Bastos
Henrik Christensen
Birgit Dusemund
Mojca Fašmon Durjava
Maryline Kouba
Marta López‐Alonso
Secundino López Puente
Francesca Marcon
Baltasar Mayo
Alena Pechová
Mariana Petkova
Fernando Ramos
Yolanda Sanz
Roberto Edoardo Villa
Ruud Woutersen
Gabriele Aquilina
Paul Brantom
Noël Dierick
Giovanna Martelli
Kettil Svensson
Montserrat Anguita
Rosella Brozzi
Jaume Galobart
Jordi Ortuño Casanova
Elisa Pettenati
Jordi Tarrés‐Call
Source :
EFSA Journal, Vol 20, Iss 12, Pp n/a-n/a (2022)
Publication Year :
2022
Publisher :
Wiley, 2022.

Abstract

Abstract Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of 6‐phytase (VTR‐phytase) as zootechnical feed additive for all pigs and all avian species. The additive VTR‐phytase consists of 6‐phytase and it is available in solid and liquid forms. VTR phytase (liquid/solid) was produced by a genetically modified strain of Komagataella phaffii (CGMCC 7.370). The genetic modification of the production strain does not give rise to safety concerns. Viable cells of the production strain and its DNA were not detected in the final products. The additive does not pose any safety concern regarding the production strain. VTR phytase (liquid/solid) produced by Komagataella phaffii CGMCC 7.370 is safe for all Suidae and all avian species at the proposed conditions of use. The use of both forms of the additive under assessment in animal nutrition under the proposed conditions of use raises no safety concerns for consumers or for the environment. The liquid VTR phytase and powder VTR phytase are non‐irritant to skin or eyes but should be considered skin and respiratory sensitisers. The additive has the potential to be efficacious in laying hens at 1,000 U phytase/kg complete feed. The conclusion can be extrapolated to other birds for egg production or breeding. The FEEDAP Panel cannot conclude on the efficacy of all pigs or growing poultry species.

Details

Language :
English
ISSN :
18314732
Volume :
20
Issue :
12
Database :
Directory of Open Access Journals
Journal :
EFSA Journal
Publication Type :
Academic Journal
Accession number :
edsdoj.347e8156dc3941519983e63e4f75bb4e
Document Type :
article
Full Text :
https://doi.org/10.2903/j.efsa.2022.7701