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Increased fMRI connectivity upon chemogenetic inhibition of the mouse prefrontal cortex

Authors :
Federico Rocchi
Carola Canella
Shahryar Noei
Daniel Gutierrez-Barragan
Ludovico Coletta
Alberto Galbusera
Alexia Stuefer
Stefano Vassanelli
Massimo Pasqualetti
Giuliano Iurilli
Stefano Panzeri
Alessandro Gozzi
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Pathological perturbation affects whole brain network activity. Here the authors show in mice that cortical inactivation unexpectedly results in increased fMRI connectivity between the manipulated regions and its direct axonal targets.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.34340a6ddc7e440f8ca5c87f67b0192c
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-28591-3