Cryo-Electron Tomography of the Herpesvirus Procapsid Reveals Interactions of the Portal with the Scaffold and a Shift on Maturation

Authors :: Michael H. C. Buch
William W. Newcomb
Dennis C. Winkler
Alasdair C. Steven
J. Bernard Heymann
Source :: mBio, Vol 12, Iss 2 (2021)
Publication Year :: 2021
Publisher :: American Society for Microbiology, 2021.
Abstract: Herpes simplex virus 1 (HSV-1) infects a majority of humans, causing mostly mild disease but in some cases progressing toward life-threatening encephalitis. Understanding the life cycle of the virus is important to devise countermeasures.

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