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Association of Euterpe oleracea, Bixa orellana, Myciaria dubia, and Astrocaryum aculeatum (the Terasen® Nutraceutical) Increases the Lifespan of Caenorhabditis elegans

Authors :
Ester Lopes de Melo
Bruno Augusto Machado Tavares
Nayara Nílcia Dias Colares
Aline Lopes do Nascimento
Helison de Oliveira Carvalho
Andrés Navarrete Castro
Arlindo César Matias Pereira
Carlos Eduardo Winter
Iracirema da Silva Sena
Luiz Fernando Moreira
José Carlos Tavares Carvalho
Source :
Journal of Ageing and Longevity, Vol 3, Iss 4, Pp 494-504 (2023)
Publication Year :
2023
Publisher :
MDPI AG, 2023.

Abstract

Aging is a complex process associated with tissue degeneration and an increased risk of age-related diseases. This study aimed to evaluate the impact of Terasen®, a nutraceutical containing standardized extracts of Euterpe oleracea, Myrciaria dubia, and purified oil of Bixa orellana and Astrocaryum aculeatum on the lifespan of Caenorhabditis elegans. The findings demonstrated that Terasen® exhibited significant radical scavenging in vitro, decreased the feeding behavior of C. elegans without affecting the animals’ final size, increased the eggs laid in a concentration-dependent fashion, although the total progeny was reduced compared to the control, and increased the median and maximum lifespan. These findings suggest that Terasen® may improve the lifespan in C. elegans, warranting further investigation.

Details

Language :
English
ISSN :
26739259
Volume :
3
Issue :
4
Database :
Directory of Open Access Journals
Journal :
Journal of Ageing and Longevity
Publication Type :
Academic Journal
Accession number :
edsdoj.340b287e73a84f43ac64b43822b94f65
Document Type :
article
Full Text :
https://doi.org/10.3390/jal3040022