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Association of Euterpe oleracea, Bixa orellana, Myciaria dubia, and Astrocaryum aculeatum (the Terasen® Nutraceutical) Increases the Lifespan of Caenorhabditis elegans
- Source :
- Journal of Ageing and Longevity, Vol 3, Iss 4, Pp 494-504 (2023)
- Publication Year :
- 2023
- Publisher :
- MDPI AG, 2023.
-
Abstract
- Aging is a complex process associated with tissue degeneration and an increased risk of age-related diseases. This study aimed to evaluate the impact of Terasen®, a nutraceutical containing standardized extracts of Euterpe oleracea, Myrciaria dubia, and purified oil of Bixa orellana and Astrocaryum aculeatum on the lifespan of Caenorhabditis elegans. The findings demonstrated that Terasen® exhibited significant radical scavenging in vitro, decreased the feeding behavior of C. elegans without affecting the animals’ final size, increased the eggs laid in a concentration-dependent fashion, although the total progeny was reduced compared to the control, and increased the median and maximum lifespan. These findings suggest that Terasen® may improve the lifespan in C. elegans, warranting further investigation.
- Subjects :
- longevity
healthspan
lifespan
nutraceuticals
C. elegans
Medicine
Subjects
Details
- Language :
- English
- ISSN :
- 26739259
- Volume :
- 3
- Issue :
- 4
- Database :
- Directory of Open Access Journals
- Journal :
- Journal of Ageing and Longevity
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.340b287e73a84f43ac64b43822b94f65
- Document Type :
- article
- Full Text :
- https://doi.org/10.3390/jal3040022