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Screening gestational diabetes mellitus: The role of maternal age.

Authors :
Chun-Heng Kuo
Szu-Chi Chen
Chi-Tai Fang
Feng-Jung Nien
En-Tzu Wu
Shin-Yu Lin
Lee-Ming Chuang
Chien-Nan Lee
Hung-Yuan Li
Source :
PLoS ONE, Vol 12, Iss 3, p e0173049 (2017)
Publication Year :
2017
Publisher :
Public Library of Science (PLoS), 2017.

Abstract

OBJECTIVE:Using a specific cutoff of fasting plasma glucose (FPG) to screen gestational diabetes mellitus (GDM) can reduce the use of oral glucose tolerance tests (OGTT). Since the prevalence of GDM increases with age, this screening method may not be appropriate in healthcare systems where women become pregnant at older ages. Therefore, we aimed to develop a screening algorithm for GDM that takes maternal age into consideration. METHODS:We included 945 pregnant women without history of GDM who received 75g OGTT to diagnose GDM in 2011. Screening algorithms using FPG with or without age were developed. Another 362 pregnant women were recruited in 2013-2015 as the validation cohort. RESULTS:Using FPG criteria alone, more GDM diagnoses were missed in women ≥35 years than in women

Subjects

Subjects :
Medicine
Science

Details

Language :
English
ISSN :
19326203
Volume :
12
Issue :
3
Database :
Directory of Open Access Journals
Journal :
PLoS ONE
Publication Type :
Academic Journal
Accession number :
edsdoj.340aca8cd3ef42478a6e48562623feee
Document Type :
article
Full Text :
https://doi.org/10.1371/journal.pone.0173049