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IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes
- Source :
- Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
- Publication Year :
- 2018
- Publisher :
- Nature Portfolio, 2018.
-
Abstract
- Most of the more than 200 known genetic risk loci for inflammatory bowel disease (IBD) reside in regulatory regions. Here, the authors provide eQTL datasets for six circulating immune cell types and ileal, colonic and rectal biopsies to map regulatory modules and identify potential causative genes for IBD.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 9
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.3282316b00248958032424db0e3a0c7
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-018-04365-8