Evaluation of epidemiologic and demographic aspects of primary biliary cirrhosis in Isfahan population from 2009 - 2017

Introdution: Primary biliary cirrhosis is a chronic cholestatic disease of the liver, characterized by the inflammation plus progressive and non-purulent destruction of the small biliary ducts, and the presence of auto antibodies against mitochondrial self-antigens. It seems that the prevalence of PBC in the western world is more than other parts of the world. This study aimed to identify all the patients with PBC in Isfahan and describe their epidemiological and demographic characteristics. Methods: The current study was a historical (retrospective) cohort investigation, which conducted between 2009 and 2017. We conducted this study by filling out questionnaires and obtaining the patients’ records and making telephone calls with previously admitted patients. Sampling was done as a census of all patients according to the study inclusion criteria. To analyze the data. SPSS software Version 16 was used and P-value