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(±)-R,S-2-Chloro-N-(4-methyl-2-oxo-2H-chromen-7-yl)-2-phenylacetamide
- Source :
- Molbank, Vol 2024, Iss 2, p M1830 (2024)
- Publication Year :
- 2024
- Publisher :
- MDPI AG, 2024.
-
Abstract
- In this study, we report the synthesis of (±)-2-chloro-N-(4-methyl-2-oxo-2H-chromen-7-yl)-2-phenylacetamide through the reaction of 7-amino-4-methyl-2H-chromen-2-one with (±)-2-chloro-2-phenylacetyl chloride. The in vitro anti-inflammatory activity of the new compound was evaluated, and the results indicated that it exhibited superior activity compared to the standard, ibuprofen. The bio-functional hybrid compound underwent thorough detailed characterization utilizing 1H and 13C NMR, UV, and mass spectral analysis.
Details
- Language :
- English
- ISSN :
- 14228599
- Volume :
- 2024
- Issue :
- 2
- Database :
- Directory of Open Access Journals
- Journal :
- Molbank
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.31d93960064aa6a5cdd5fbed60de16
- Document Type :
- article
- Full Text :
- https://doi.org/10.3390/M1830