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Impact of a vaccination programme in children vaccinated with ProQuad, and ProQuad-specific effectiveness against varicella in the Veneto region of Italy

Authors :
Carlo Giaquinto
Giovanni Gabutti
Vincenzo Baldo
Marco Villa
Lara Tramontan
Nadia Raccanello
Francesca Russo
Chiara Poma
Antonio Scamarcia
Luigi Cantarutti
Rebecca Lundin
Emilia Perinetti
Xavier Cornen
Stéphane Thomas
Céline Ballandras
Audrey Souverain
Susanne Hartwig
Source :
BMC Infectious Diseases, Vol 18, Iss 1, Pp 1-9 (2018)
Publication Year :
2018
Publisher :
BMC, 2018.

Abstract

Abstract Background Monovalent varicella vaccines have been available in the Veneto Region of Italy since 2004. In 2006, a single vaccine dose was added to the immunisation calendar for children aged 14 months. ProQuad®, a quadrivalent measles-mumps-rubella-varicella vaccine, was introduced in May 2007 and used, among other varicella vaccines, until October 2008. This study aimed to evaluate the effectiveness of a single dose of ProQuad, and the population impact of a vaccination program (VP) against varicella of any severity in children who received a first dose of ProQuad at 14 months of age in the Veneto Region, Methods All children born in 2006/2007, i.e., eligible for varicella vaccination after ProQuad was introduced, were retrospectively followed through individual-level data linkage between the Pedianet database (varicella cases) and the Regional Immunization Database (vaccination status). The direct effectiveness of ProQuad was estimated as the incidence rate of varicella in ProQuad-vaccinated children aged

Details

Language :
English
ISSN :
14712334
Volume :
18
Issue :
1
Database :
Directory of Open Access Journals
Journal :
BMC Infectious Diseases
Publication Type :
Academic Journal
Accession number :
edsdoj.31250fd2c55347ffb019b1efc6ecfcb9
Document Type :
article
Full Text :
https://doi.org/10.1186/s12879-018-3017-9