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Correlation of Intraprocedural and Follow Up Parameters for Mitral Regurgitation Grading after Percutaneous Edge-to-Edge Repair

Authors :
Eduardo Pozo Osinalde
Alejandra Salinas Gallegos
Ximena Gordillo
Luis Nombela Franco
Pedro Marcos-Alberca
Patricia Mahía
Gabriela Tirado-Conte
José Juan Gómez de Diego
Pilar Jiménez Quevedo
Antonio Fernández-Ortíz
Julián Pérez-Villacastín
Jose Alberto de Agustín Loeches
Source :
Journal of Clinical Medicine, Vol 11, Iss 9, p 2276 (2022)
Publication Year :
2022
Publisher :
MDPI AG, 2022.

Abstract

Background: There is no consensus on the best intraprocedural parameter to evaluate residual mitral regurgitation (MR) after transcatheter edge-to-edge mitral repair (TEER). Thus, our aim was to evaluate the predictive value of different MR parameters from intraprocedural transesophageal echocardiogram (TEE) for grading in consecutive transthoracic echocardiogram (TTE) during the follow up. Methods: All the consecutive patients who underwent TEER with MitraClip between 2010 and 2020 in our center were considered. TEE-derived immediate postprocedural MR parameters were reassessed to blindly compare them with follow up MR grading in sequential TTE. Results: We finally included 88 patients (64.8% males; 76 ± 10 years-old). Significant MR was detected in 14.3% of the cases at 6 months, in similar proportion than at postprocedural at 1 month. Among all the intraprocedural TEE quantitative parameters only additive and maximum VC were associated with significant MR persistence. Moreover, on ROC analysis maximum VC demonstrated an excellent discriminatory power (AUC 0.96; p < 0.001) to identify MR ≥ III at 6 months. Thus, a cut-off point of 0.45 cm demonstrated 88% sensitivity and 89% specificity. Conclusion: Among intraprocedural TEE parameters to evaluate residual MR in TEER, maximum and additive VC were the most reliable to predict persistence of significant insufficiency.

Details

Language :
English
ISSN :
20770383
Volume :
11
Issue :
9
Database :
Directory of Open Access Journals
Journal :
Journal of Clinical Medicine
Publication Type :
Academic Journal
Accession number :
edsdoj.31198152cf14d23983d5de8994e02ea
Document Type :
article
Full Text :
https://doi.org/10.3390/jcm11092276