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Radionuclide synovectomy – essentials for rheumatologists

Radionuclide synovectomy – essentials for rheumatologists

Authors :
Marek M. Chojnowski
Anna Felis-Giemza
Małgorzata Kobylecka
Source :
Rheumatology, Vol 54, Iss 3, Pp 108-116 (2016)
Publication Year :
2016
Publisher :
Termedia Publishing House, 2016.

Abstract

Radionuclide synovectomy is a minimally invasive method of treating persistent joint inflammation. It involves intra-articular injection of radioactive colloids which induce necrosis and fibrosis of hypertrophic synovial membrane. The most common indication for radiosynovectomy is rheumatoid arthritis, although patients with seronegative spondyloarthropathies, unclassified arthritis, haemophilic arthropathy and other less common arthropathies can also benefit from this method. Radiosynovectomy is safe, well tolerated and efficacious. About 70–80% of patients respond well to the therapy. However, the therapeutic effects are considerably worse in patients with co-existent osteoarthritis and advanced joint degeneration. Despite its advantages, radionuclide synovectomy is not performed as often as it could be, so greater knowledge and understanding of this method are needed. The authors present the most important facts about radiosynovectomy that may help rheumatologists in their daily clinical practice.

Details

Language :
English
ISSN :
00346233 and 20849834
Volume :
54
Issue :
3
Database :
Directory of Open Access Journals
Journal :
Rheumatology
Publication Type :
Academic Journal
Accession number :
edsdoj.30ba5242306547abb403523a32af66b6
Document Type :
article
Full Text :
https://doi.org/10.5114/reum.2016.61210