Cefepime-Resistant Pseudomonas aeruginosa

Authors :: Ehimare Akhabue
Marie Synnestvedt
Mark G. Weiner
Warren B. Bilker
Ebbing Lautenbach
Source :: Emerging Infectious Diseases, Vol 17, Iss 6, Pp 1037-1043 (2011)
Publication Year :: 2011
Publisher :: Centers for Disease Control and Prevention, 2011.
Abstract: Resistance to extended-spectrum cephalosporins complicates treatment of Pseudomonas aeruginosa infections. To elucidate risk factors for cefepime-resistant P. aeruginosa and determine its association with patient death, we conducted a case–control study in Philadelphia, Pennsylvania. Among 2,529 patients hospitalized during 2001–2006, a total of 213 (8.4%) had cefepime-resistant P. aeruginosa infection. Independent risk factors were prior use of an extended-spectrum cephalosphorin (p