Bryozoans, the remedy hidden treasures of oceans: secondary metabolites

Bryozoans, commonly known as “moss animals”, are typically aquatic, filter feeding, sessile, colonial marine animals. Although, they are a rich resource of new bioactive secondary metabolites, but studies on their secondary metabolite have been neglected. Although over 8000 species are known, the lowest numbers of novel compounds were isolated from the phylum Bryozoa. In addition, presently nothing is recognized regarding the origin of the bioactive compounds isolated by bryozoans. At present nothing is known regarding the origin of the natural products isolated by bryozoans. The most famous of compounds obtained from these organisms are macrolide lactones of Bryostatins. They are potent modulators of protein kinase C. The amazing compounds such as Flustramines, Hinckdentine, Convolutamines, Kororamides, Chatellines, Chartellamides, Convolutamines, Convolutamidines, euthyroideone, amathaspiramide, lutamides, Volutamides, tambjamines, Phidolopins, and dozens of other compounds with different biological properties have been obtained. Very few studies have been done on these treasures in the sea depth, and more studies need to be done on them for access to their secondary metabolites.