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Potential Biomarkers of Colorectal Adenoma–Dysplasia–Carcinoma Progression: mRNA Expression Profiling and In Situ Protein Detection on TMAs Reveal 15 Sequentially Upregulated and 2 Downregulated Genes

Authors :
Orsolya Galamb
Ferenc Sipos
Sándor Spisák
Barnabás Galamb
Tibor Krenács
Gábor Valcz
Zsolt Tulassay
Béla Molnár
Source :
Cellular Oncology, Vol 31, Iss 1, Pp 19-29 (2009)
Publication Year :
2009
Publisher :
Hindawi Limited, 2009.

Abstract

Background: As most colorectal cancers (CRC) develop from villous adenomas, studying alterations in gene expression profiles across the colorectal adenoma–dysplasia–carcinoma sequence may yield potential biomarkers of disease progression.

Details

Language :
English
ISSN :
15705870 and 18758606
Volume :
31
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Cellular Oncology
Publication Type :
Academic Journal
Accession number :
edsdoj.2eb1a7a00a1b4d33abe493a1416bd8a8
Document Type :
article
Full Text :
https://doi.org/10.3233/CLO-2009-0458