Back to Search Start Over

Zone-specific reference ranges of fetal adrenal artery Doppler indices: a longitudinal study

Zone-specific reference ranges of fetal adrenal artery Doppler indices: a longitudinal study

Authors :
Ran Xu
Ziling Zhu
Wenjuan Tang
Qichang Zhou
Shi Zeng
Source :
BMC Pregnancy and Childbirth, Vol 20, Iss 1, Pp 1-8 (2020)
Publication Year :
2020
Publisher :
BMC, 2020.

Abstract

Abstract Background The fetal adrenal gland is a highly vascularized organs and develops two recognizable distinct zones in uetro, inner fetal zone (FZ) and outer definitive zone (DZ). Based on the region supplied, middle adrenal artery (MAA) mainly contribute to FZ while inferior adrenal artery (IAA) mainly to the inferior part of DZ. The purpose of this study was to establish reference ranges of adrenal artery Doppler indices of IAA and MAA, and assess zonal difference of blood supply to fetal adrenal gland. Methods The pulsatility index (PI), resistance index (RI), and systolic:diastolic ratio (S/D) of the IAA and MAA were obtained serially at 4-week intervals in normal fetuses. The MAA and IAA were referred based on the course and location in the gland: IAA referring the artery that mainly branches from the renal artery and walks along the renal upper pole, distributing the inferoposterior part of DZ in the adrenal gland while MAA as arterial blood flowing along the single central adrenal vein in the medial part of the gland. Multilevel modeling was performed to establish the gestational age-associated reference ranges for IAA and MAA. Differences in Doppler indices between the IAA and MAA were assessed. Results One hundred sixty-eight fetuses with 843 observations were included. The IAA had a higher detection rate than the MAA (100% vs 89.2%, p

Details

Language :
English
ISSN :
14712393
Volume :
20
Issue :
1
Database :
Directory of Open Access Journals
Journal :
BMC Pregnancy and Childbirth
Publication Type :
Academic Journal
Accession number :
edsdoj.2daac9edfa848aebf242f3db09352fa
Document Type :
article
Full Text :
https://doi.org/10.1186/s12884-020-03480-z