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Imaging modalities in keratoconus
- Source :
- Indian Journal of Ophthalmology, Vol 61, Iss 8, Pp 394-400 (2013)
- Publication Year :
- 2013
- Publisher :
- Wolters Kluwer Medknow Publications, 2013.
-
Abstract
- Diagnosis of keratoconus has greatly improved from simple clinical diagnosis with the advent of better diagnostic devices like corneal topographers based on placido disc, elevation based topographers and lately optical coherence tomography (OCT). These instruments are quite sensitive to pick up early keratoconus, which could help refractive surgeons to avoid serious complications like ectasia following keratorefractive surgeries. Each of these instruments has their advantages and disadvantages; in spite of that each one of them has its own place in the clinical practice. Currently, placido disc based topographers are the most commonly used topographers all over the world. There are many different companies making such devices, which follow the different techniques and color for the display. Due to these differences they are not directly comparable to each other. Various quantitative indices based on these topographers have been suggested and validated by different authors to aid in the diagnosis and quantification of keratoconus. OCT with its higher resolution and deeper penetration has created its place in the diagnostic armamentarium for keratoconus.
- Subjects :
- Epidemiology
keratoconus
prevalence
Disease pathogenesis
genetic heterogeneity
genetics and genomics
genome-wide association study
genomic loci
linkage mapping
molecular mechanisms
whole exome-genome sequencing
Deregulation
ectasia
gene expression
mass spectroscopy
proteomics
signaling pathways
Cornea
crosslinking
modulus
Corneal topography
imaging
optical coherence tomography
placido disc based topography
Ophthalmology
RE1-994
Subjects
Details
- Language :
- English
- ISSN :
- 03014738 and 19983689
- Volume :
- 61
- Issue :
- 8
- Database :
- Directory of Open Access Journals
- Journal :
- Indian Journal of Ophthalmology
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.2d8ff5d3185742d1b5da52a4b49d3172
- Document Type :
- article
- Full Text :
- https://doi.org/10.4103/0301-4738.116058