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Scar-Free Healing: Current Concepts and Future Perspectives

Scar-Free Healing: Current Concepts and Future Perspectives

Authors :
Alexandra Elena Stoica
Alexandru Mihai Grumezescu
Anca Oana Hermenean
Ecaterina Andronescu
Bogdan Stefan Vasile
Source :
Nanomaterials, Vol 10, Iss 11, p 2179 (2020)
Publication Year :
2020
Publisher :
MDPI AG, 2020.

Abstract

Every year, millions of people develop scars due to skin injuries after trauma, surgery, or skin burns. From the beginning of wound healing development, scar hyperplasia, and prolonged healing time in wound healing have been severe problems. Based on the difference between adult and fetal wound healing processes, many promising therapies have been developed to decrease scar formation in skin wounds. Currently, there is no good or reliable therapy to cure or prevent scar formation. This work briefly reviews the engineering methods of scarless wound healing, focusing on regenerative biomaterials and different cytokines, growth factors, and extracellular components in regenerative wound healing to minimize skin damage cell types, and scar formation.

Details

Language :
English
ISSN :
20794991
Volume :
10
Issue :
11
Database :
Directory of Open Access Journals
Journal :
Nanomaterials
Publication Type :
Academic Journal
Accession number :
edsdoj.2d3b6d0d800f45718ccadedc6227e120
Document Type :
article
Full Text :
https://doi.org/10.3390/nano10112179