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Characterization of SARS-CoV-2 Omicron spike RBD reveals significantly decreased stability, severe evasion of neutralizing-antibody recognition but unaffected engagement by decoy ACE2 modified for enhanced RBD binding

Authors :
Sheng Lin
Zimin Chen
Xindan Zhang
Ao Wen
Xin Yuan
Chongzhang Yu
Jing Yang
Bin He
Yu Cao
Guangwen Lu
Source :
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-3 (2022)
Publication Year :
2022
Publisher :
Nature Publishing Group, 2022.

Details

Language :
English
ISSN :
20593635
Volume :
7
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Signal Transduction and Targeted Therapy
Publication Type :
Academic Journal
Accession number :
edsdoj.2d3b4cd8bdb47b6a899b08fb5647f24
Document Type :
article
Full Text :
https://doi.org/10.1038/s41392-022-00914-2