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Cellular and physiological circadian mechanisms drive diurnal cell proliferation and expansion of white adipose tissue

Authors :
Aleix Ribas-Latre
Rafael Bravo Santos
Baharan Fekry
Yomna M. Tamim
Samay Shivshankar
Alaa M. T. Mohamed
Corrine Baumgartner
Christopher Kwok
Claudia Gebhardt
Angielyn Rivera
Zhanguo Gao
Kai Sun
John T. Heiker
Brad E. Snyder
Mikhail G. Kolonin
Kristin L. Eckel-Mahan
Source :
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

During the expansion of adipose tissue adipocyte progenitor cells proliferate and undergo adipogenesis. Here, the authors show that adipocyte progenitor cell proliferation in visceral adipose tissue has a diurnal pattern, which is dependent on both energy intake and the circadian clock.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.2bcdacfb8da49f1947d4b6f3b07213c
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-021-23770-0