The Evaluation Of 6 And 12 Hour Urine Collection For Assessing Proteinuriu In The Hypertensive Gravida

The objective of this study was to determine wether a urine collection of less than 24 hours duration accurately assesses the level of preteinuria in inpatients being evaluated for preeclampsia."nMaterials and Methods: Patients admitted to the Mirza Kouchak-Khan hospital between years 2001 to 2002, underwent 3 consecutive collections consisting of two 6 hour and one 12 hour collection. Each volume, and urine creatinine. A concurrent serum creatinine value was obtained. The protein: creatinine ratio and creatine clearance were calculated. Pearson's correlation/sensitivity, specificity and positive and negative predictive values were assessed."nResults: A total of 32 patients (98%) were preeclamptic. Total protein and serum creatinine were significantly correlated and the protein: creatinine ratio was moderately correlated between the collections. The 1st 6 hours collection (8 Am to 2 pm) had a sensitivity and specificity of 100%. The second 6 hours had a sensitivity and specificity of 96% and 86.6%. The first 12 hours had a sensitivity and specificity of 100% and 93.2%. The 2 nd 12 hours (8 Am to 8 pm) had a sensitivity and specificity of 80% and 93.3% respectively. There was a significant diurnal pattern of proteinuria."nConclusion: In conclusion based on the results achieved it can be concluded that a 6 and 12 hours urine collection/especially the first 6 hours after patient awakening can accurately assess proteinuria in the hypertensive gravida.