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Endothelial PDGF-CC regulates angiogenesis-dependent thermogenesis in beige fat
- Source :
- Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
- Publication Year :
- 2016
- Publisher :
- Nature Portfolio, 2016.
-
Abstract
- Cold-induced activation of thermogenesis in white adipose tissue (WAT), or ‘beiging’, is associated with WAT angiogenesis. Here the authors show that PDGF-CC is secreted from endothelial cells in the context of WAT angiogenesis and its paracrine action on adipocytes contributes to cold-induced beiging.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723 and 14440407
- Volume :
- 7
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.2b7dcc14440407294f031a92cd4d4a9
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/ncomms12152