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Molecular basis of mEAK7-mediated human V-ATPase regulation

Authors :
Rong Wang
Yu Qin
Xiao-Song Xie
Xiaochun Li
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Structural basis of V-ATPase regulation by endogenous proteins is unclear. Here, the authors find mEAK7 as an endogenous V-ATPase modulator and determine its structure with V-ATPase, suggesting the potential role of mEAK7 in V-ATPase regulation.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.2ad8ef325bc94c018b857cdbfefda4ea
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-30899-z