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6-(3,5-Dimethylbenzyl)-5-ethyl-1-[(2-phenylethoxy)methyl]pyrimidine-2,4(1H,3H)dione

Authors :
Nasser R. El-Brollosy
Mohamed I. Attia
Hazem A. Ghabbour
Suchada Chantrapromma
Hoong-Kun Fun
Source :
Acta Crystallographica Section E, Vol 68, Iss 4, Pp o1031-o1032 (2012)
Publication Year :
2012
Publisher :
International Union of Crystallography, 2012.

Abstract

In the title pyrimidine derivative, C24H28N2O3, the uracil unit is essentially planar with an r.m.s. deviation of 0.0054 (1) Å for the eight non-H atoms. The pyrimidine ring is tilted by a dihedral angle of 77.08 (7)° with respect to the aromatic ring of the 3,5-dimethylbenzyl substituent, whereas it is nearly parallel to the benzene ring of the phenethoxymethyl unit, with a dihedral angle of 8.17 (8)°. An intramolecular C—H...O hydrogen bond generates an S(6) ring motif. In the crystal, molecules are linked by a pair of amide–uracil N—H...O hydrogen bonds into an inversion R22(8) dimer. These dimers are stacked along the b axis through π–π interactions with a centroid–centroid distance of 3.9517 (8) Å. Weak C—H...π interactions are also present.

Subjects

Subjects :
Crystallography
QD901-999

Details

Language :
English
ISSN :
16005368
Volume :
68
Issue :
4
Database :
Directory of Open Access Journals
Journal :
Acta Crystallographica Section E
Publication Type :
Academic Journal
Accession number :
edsdoj.2a40719fc1654050b4ec6694289c0d6f
Document Type :
article
Full Text :
https://doi.org/10.1107/S1600536812009841