Temporal analysis of Tuberculosis-HIV coinfection cases in a state of northeast Brazil

Background and Objectives: Tuberculosis-HIV co-infection (TB/HIV) has been an important cause of death and medical hospital-outpatient care in health services worldwide. Thus, the objective of this study was to evaluate the behavior of TB/HIV coinfection in the state of Alagoas, Brazil. Methods: This is an ecological, time-series study that analyzed indicators of TB/HIV co-infection between 2001 and 2016. The study area was the state of Alagoas, Brazil, and its administrative divisions of reference for the health sector. The analysis of the temporal evolution used percent variance and the Mann-Kendall trend test. Results: In the period from 2001 to 2016, 996 new cases of TB/HIV coinfection were reported in Alagoas, corresponding to 5.6% of the total TB cases. The percentage of TB/HIV coinfection increased from 1.4% in 2001 to 14.6% in 2016, with 1180% (p