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Secretory Carcinoma of the Upper Lip: A Case Report and Review of the Literature

Authors :
Yousef Hammad, DMD
Ali Edrisi, DMD, MS
Timothy W. Neal, DDS
Yisheng Fang, MD, PhD
Thomas Schlieve, DDS, MD
Source :
Oral and Maxillofacial Surgery Cases, Vol 7, Iss 4, Pp 100236- (2021)
Publication Year :
2021
Publisher :
Elsevier, 2021.

Abstract

Secretory carcinoma (SC), formerly known as mammary analogue secretory carcinoma (MASC), is a rare salivary gland tumor that was first described by Skalova et al., in 2010 [1]. Thirty-two cases of SC involving the lips have been reported in the literature. The current report describes a case of SC discovered in the upper lip of a 20-year-old-female. The lesion was excised, and the pathology report returned as SC with positive margins. One month later, the patient was treated with radical excision of the lesion with 1cm margins, and the pathology report described SC of the inner aspect of the right side of the upper lip that was unifocal, 0.3cm in size with a 3mm depth of invasion. The margins were uninvolved by the invasive tumor, and the distance from the closest margin was at least 5mm to the deep margin. No lymphovascular invasion or perineural invasion was identified. The tumor cells were positive for mammaglobin, S100, and GATA-3. The purpose of this report is to highlight the presentation and review the morphologic and immunohistochemical features of SC. Our aim is to add to the existing body of literature and present an extremely rare case of SC of the upper lip.

Details

Language :
English
ISSN :
22145419
Volume :
7
Issue :
4
Database :
Directory of Open Access Journals
Journal :
Oral and Maxillofacial Surgery Cases
Publication Type :
Academic Journal
Accession number :
edsdoj.29428b6a621d4585853ef85f2ad8cde9
Document Type :
article
Full Text :
https://doi.org/10.1016/j.omsc.2021.100236