Study of microbial Activity of Some Arylorganomercury ( II ) Derivatives Containing Amino Group on Some Pathogenic Isolated Bacteria

Abstract :The aim of this study was to evaluate a microbial activity of the three organomercury compounds : 2-amino-5-methylphenyl mercury(II)chloride 1 , 2-amino-5-bromophenyl mercury(II)chloride 2 and 2-amino-5-nitrophenyl mercury(II)chloride 3 which were synthesized and characterized by various physical techniques . It have been reported to have antimicrobial activity against six various bacteria such as Gram positive bacteria ( Staphylococcus aureus and Bacillus subtilis ) and Gram negative bacteria ( Escherichia coli , Klebsiella spp. , Salmonella spp. and Pseudomonas spp. ) . The concentrations of above compounds 1 , 2 and 3 were ( 0.5 , 0.3 – 0.5 and 0.3 – 0.5 milligram / milliliter ) found to be more effective concentrations than others related with the inhibition zone respectively . The order of antimicrobial activity for the studied compounds were depending on the power of the drawing group with mercury moiety and amino group abreast in the aromatic skeleton – structure . So , the order is NO 2 ( 3 ) > Br ( 2 ) > CH 3 ( 1 )