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Gut to lung translocation and antibiotic mediated selection shape the dynamics of Pseudomonas aeruginosa in an ICU patient

Authors :
Rachel M. Wheatley
Julio Diaz Caballero
Thomas E. van der Schalk
Fien H. R. De Winter
Liam P. Shaw
Natalia Kapel
Claudia Recanatini
Leen Timbermont
Jan Kluytmans
Mark Esser
Alicia Lacoma
Cristina Prat-Aymerich
Antonio Oliver
Samir Kumar-Singh
Surbhi Malhotra-Kumar
R. Craig MacLean
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

In this paper the authors show that the pathogenic bacterium Pseudomonas aeruginosa migrates between the gut and lungs of an ICU patient, and that differential evolutionary responses to antibiotic treatment occur in these organs.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.280702e25b8c44b686037446fff256f7
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-34101-2