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mTORC2 confers neuroprotection and potentiates immunity during virus infection

Authors :
Rahul K. Suryawanshi
Chandrashekhar D. Patil
Alex Agelidis
Raghuram Koganti
Joshua M. Ames
Lulia Koujah
Tejabhiram Yadavalli
Krishnaraju Madavaraju
Lisa M. Shantz
Deepak Shukla
Source :
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

The immune response to herpes simplex virus is essential in limiting immunopathology during infection, however factors linked to neuroprotection are currently unclear. Here the authors implicate mTORC2 in the host response to viral infection and link to neuroprotection.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.27f4f68e4f724618b102cf6fe1166fed
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-021-26260-5