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Protein Z modulates the metastasis of lung adenocarcinoma cells

Authors :
Peng Jin
Yang Kai-Ying
Li Huan
Zheng Shan-Shan
Pan Xue-Yi
Source :
Open Life Sciences, Vol 18, Iss 1, Pp 7-33 (2023)
Publication Year :
2023
Publisher :
De Gruyter, 2023.

Abstract

Epithelial–mesenchymal transition (EMT)-related proteins (Slug, vimentin, and N-cadherin) are downregulated by Protein Z silencing, which significantly prohibits cellular proliferation and EMT activity (decrease of cellular migration and invasion) in non-small-cell lung cancer cells.

Subjects

Subjects :
protein z
non-small cell lung cancer cells
metastasis
invasion
epithelial–mesenchymal transition pathway
Biology (General)
QH301-705.5

Details

Language :
English
ISSN :
23915412
Volume :
18
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Open Life Sciences
Publication Type :
Academic Journal
Accession number :
edsdoj.2771aa4f19642ff96a25451c2fcfd85
Document Type :
article
Full Text :
https://doi.org/10.1515/biol-2022-0667
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