Back to Search Start Over

Installation of -SO2F groups onto primary amides

Authors :
Jing Liu
Shi-Meng Wang
Njud S. Alharbi
Hua-Li Qin
Source :
Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 1907-1912 (2019)
Publication Year :
2019
Publisher :
Beilstein-Institut, 2019.

Abstract

A protocol of SO2F2-mediated installation of sulfonyl fluoride onto primary amides has been developed providing a new portal to sulfur(VI) fluoride exchange (SuFEx) click chemistry. The generated molecules contain pharmaceutically important amide and -SO2F moieties for application in the discovery of new therapeutics.

Details

Language :
English
ISSN :
18605397
Volume :
15
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Beilstein Journal of Organic Chemistry
Publication Type :
Academic Journal
Accession number :
edsdoj.2724d7c05703494bb8a1f7d5b0671910
Document Type :
article
Full Text :
https://doi.org/10.3762/bjoc.15.186