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Methylation profiling identifies two subclasses of squamous cell carcinoma related to distinct cells of origin
- Source :
- Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
- Publication Year :
- 2018
- Publisher :
- Nature Portfolio, 2018.
-
Abstract
- Cutaneous squamous cell carcinoma (cSCC) is a skin cancer that normally progresses from UV-induced actinic keratosis (AK). Here, the authors investigate the epigenomics of cSCC and highlight two distinct subclasses of AK and cSCC originating from distinct keratinocyte differentiation stages.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 9
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.26b413b8fcbb4405904d85c489f5f2a2
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-018-03025-1