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Early-life social experience affects offspring DNA methylation and later life stress phenotype

Authors :
Zachary M. Laubach
Julia R. Greenberg
Julie W. Turner
Tracy M. Montgomery
Malit O. Pioon
Maggie A. Sawdy
Laura Smale
Raymond G. Cavalcante
Karthik R. Padmanabhan
Claudia Lalancette
Bridgett vonHoldt
Christopher D. Faulk
Dana C. Dolinoy
Kay E. Holekamp
Wei Perng
Source :
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

Early social experience can alter epigenetic patterns and stress responses later in life. A study on wild spotted hyenas finds that maternal care and social connections after leaving the den influence DNA methylation and contribute to a developmentally plastic stress response.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.26a7708842bf456a9e9e486a8e5289da
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-021-24583-x