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Ureteral Stent and Percutaneous Nephrostomy in Managing Malignant Ureteric Obstruction of Gastrointestinal Origin: A 10 Years’ Experience

Authors :
Elisa De Lorenzis
Elena Lievore
Matteo Turetti
Andrea Gallioli
Barbara Galassi
Luca Boeri
Emanuele Montanari
Source :
Gastrointestinal Disorders, Vol 2, Iss 4, Pp 456-468 (2020)
Publication Year :
2020
Publisher :
MDPI AG, 2020.

Abstract

Background: Malignant ureteral obstruction (MUO) is variable in presentation and there is no consensus on its management, especially when caused by gastrointestinal (GI) malignancies. Our aim was to describe our experience with this oncological complication. Methods: We retrospectively analyzed the outcomes of ureteral stent and nephrostomy tube (NT) positioning for GI-related MUO from 2010 to 2020. We performed descriptive analysis, survival analysis, and uni- and multi-variate analysis. Results: We included 51 patients. NT was mainly used when bladder involvement occurred and when MUO revealed an ex novo cancer diagnosis. Survival was poorer in patients with new diagnoses and in those receiving no treatment after decompression. Moreover, MUO caused by upper-GI tumors was related to shorter overall survival. Conclusions: GI tumors causing MUO should be considered of poor prognosis. Treatment decisions should be weighted accurately by both specialists and the patient.

Details

Language :
English
ISSN :
26245647
Volume :
2
Issue :
4
Database :
Directory of Open Access Journals
Journal :
Gastrointestinal Disorders
Publication Type :
Academic Journal
Accession number :
edsdoj.26350bc3f4b45ada97b315f67c150
Document Type :
article
Full Text :
https://doi.org/10.3390/gidisord2040041